Nakapiripirit District is a district in Northern Uganda. Like many other Ugandan districts, it is named after its 'chief town', Nakapiripirit, where the district headquarters are located. 

Formerly part of Moroto District, in 1974 Nakapiripirit existed as south Karamoja District, but was in 1980 merged with Central Karamoja to form Moroto District. IN 2001, it was again carved out of Moroto District.

• Location

The district is bordered by Napak District to the north, Moroto District to the northeast, Amdudat to the east Katakwi in the Northwest, Sironko and Kapchorwa in the south, Kween District to the southeast, Bulambuli District to the southwest, and Kumi District to the west. Nakapiripirit, the main municipal, administrative and commercial center in the district, lies approximately 125 kilometres (78 mi), by road, northeast of Mbale, the nearest large town. This location lies approximately 360 kilometres (220 mi), by road, northeast of Kampala, the capital of Uganda and the largest city in that country. The coordinates of the district are:01 55N, 34 40E.

• Population

The 1991 national population census estimated the district population at about 66,250. In 2002, the national census conducted that year estimated the population of the district at about 90,920. Between 2002 and 2012, it is estimated that the district population has been growing at an annual rate of 6%. In view of those data, it is estimated that in 2012 the population of Nakapiripirit District was about 161,600.

• Ethnicities

The majority of the population are Karamojong and the language spoken is the Karamojong language.

• Economic activity

The main activity in the district is animal husbandry and the majority of the population are pastoralists. However in some areas, especially in the south, some agricultural activity takes place. More recently the exploration of the rich mineral landscape has begun in earnest by American, Canadian, Middle Eastern and Indian prospectors.